Syndrome needs at least NVIDIA GeForce GTX 260 / AMD Radeon HD 5750. OpenGL 3.3, and NVIDIA GeForce GTX 480 / AMD Radeon HD 5970. OpenGL 3.3 is recommended. Enter your graphics card and processor above to see your estimated FPS, or check your whole Steam library at once.

What are the system requirements for Syndrome?

Minimum: graphics NVIDIA GeForce GTX 260 / AMD Radeon HD 5750. OpenGL 3.3, processor Core i3 / AMD A6 2.4Ghz, RAM 4 GB RAM. Recommended graphics card: NVIDIA GeForce GTX 480 / AMD Radeon HD 5970. OpenGL 3.3.

Can I run Syndrome?

Syndrome needs at least NVIDIA GeForce GTX 260 / AMD Radeon HD 5750. OpenGL 3.3, and NVIDIA GeForce GTX 480 / AMD Radeon HD 5970. OpenGL 3.3 is recommended. Below: estimated FPS for popular graphics cards and a free check for your own PC.

ReleaseOct 6, 2016
Steam user reviews70 % positive
ProtonDBbronze

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Will it run on my PC?

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Syndrome system requirements

	Minimum	Recommended
OS	Windows Vista 64-bit	Windows 7 64-bit
Processor	Core i3 / AMD A6 2.4Ghz	Core i5 / AMD FX 2.4Ghz
Graphics	NVIDIA GeForce GTX 260 / AMD Radeon HD 5750. OpenGL 3.3	NVIDIA GeForce GTX 480 / AMD Radeon HD 5970. OpenGL 3.3
Memory	4 GB RAM	8 GB RAM
Storage	9 GB available space	9 GB available space

Estimated FPS in Syndrome

High settings, no upscaling, with a fast processor (Ryzen 7 7800X3D). Estimates from the game's requirements, not benchmarks.

Not yet checked against benchmarks, a rough estimate that can be off by 25 % or more.

Graphics card	1080p	1440p	4K
GTX 1060 6GB	272	201	122
GTX 1660 Super	389	288	175
RTX 2060	450	333	203
RTX 3060	500+	446	271
RTX 4060	500+	481	293
RTX 4060 Ti 8GB	500+	500+	346
RTX 4060 Ti 16GB	500+	500+	346
RTX 5060	500+	500+	354
RTX 5060 Ti 8GB	500+	500+	407
RTX 5060 Ti 16GB	500+	500+	407
RX 9060 XT	500+	500+	380
RTX 3070	500+	500+	380
RTX 4070	500+	500+	466
RTX 5070	500+	500+	500+
RX 7800 XT	500+	500+	489
RX 9070 XT	500+	500+	500+
RTX 5070 Ti	500+	500+	500+
RTX 4080	500+	500+	500+
RTX 5080	500+	500+	500+
RTX 4090	500+	500+	500+
RTX 5090	500+	500+	500+

How we estimate FPS →

Which graphics card do I need for Syndrome?

The cheapest current graphics card that reaches each goal, paired with a fast processor.

1080p High · 60 FPSIntel Arc B580 12 GB ~500 FPSView on Amazon ↗
1440p High · 60 FPSIntel Arc B580 12 GB ~481 FPSView on Amazon ↗
1440p High · 144 FPSIntel Arc B580 12 GB ~481 FPSView on Amazon ↗
4K High · 60 FPSIntel Arc B580 12 GB ~293 FPSView on Amazon ↗

Prices change often, check the current price in the store. Price check: 10/7/2026.

Best graphics card for Syndrome, every GPU ranked →

Optimize and fix performance

Deeper guides and known fixes for Syndrome, straight from the communities and databases PC players trust. We link out, so every tip comes from the real source.

Frequently asked questions

Can I run Syndrome?: Syndrome needs at least NVIDIA GeForce GTX 260 / AMD Radeon HD 5750. OpenGL 3.3, and NVIDIA GeForce GTX 480 / AMD Radeon HD 5970. OpenGL 3.3 is recommended. Enter your graphics card and processor above to see your estimated FPS, or check your whole Steam library at once.
What are the system requirements for Syndrome?: Minimum: graphics NVIDIA GeForce GTX 260 / AMD Radeon HD 5750. OpenGL 3.3, processor Core i3 / AMD A6 2.4Ghz, RAM 4 GB RAM. Recommended graphics card: NVIDIA GeForce GTX 480 / AMD Radeon HD 5970. OpenGL 3.3.